To start - Go talk to some of the MIT doctoral candidates that the books have programming their Cray XC40's.
Because baseball has twice as many data points as hockey and hoops (10 times football), and with stats now being done to the micro pitch, the machines can only be beat by something intuitive (you better be a savant) or a system that uses the machines like:
1. follow the Market
2. beat Market to the Closer
I'm certain Number 2 is extremely difficult.
BOL