No more cupcake schedule once you're the champ. There's a reason its so hard to repeat. Outside of their division, which is already bloodthirsty, they have a tough road with the week 4 bye then 13 straight games with 4 of the last 7 on the road. I wouldn't be surprised if the Cardinals and Niners take the division and the Wildcard.
As for Indy, betting on anyone but Broncos or Patriots to take the AFC is risky, and beating the NFC in the big one is far out.